| 1. | The Mannich reaction is also considered a condensation reaction.
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| 2. | Mannich reaction with dimethylamine and formaldehyde was described.
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| 3. | Overman has also worked extensively on the aza-Cope-Mannich reaction, originally designed
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| 4. | A related reaction is the Mannich reaction.
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| 5. | Like the Mannich reaction, aldehydes give good yields while ketones tend to give lower conversion.
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| 6. | This is suitable for cleaving glycols and alpha-hydroxy ketones in ring opening and Mannich reaction.
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| 7. | In the Mannich reaction, primary or secondary amines or ammonia, are employed for the activation of formaldehyde.
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| 8. | Gramine, a useful synthetic intermediate, is produced via a Mannich reaction of indole with dimethylamine and formaldehyde.
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| 9. | Additional reactions include aldol reactions, Mannich reaction, Michael reaction, amination, ?-oxyamination, and ?-halogenation.
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| 10. | The Mannich reaction is an example of nucleophilic addition of an amine to a carbonyl group followed by dehydration to the Schiff base.
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